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Mississippi River Gateway Cruise
(St. Louis to New Orleans)

11 days with American Cruise Lines  Rating: Deluxe

Book this River Cruise Now and Save!


  • Save $1,200 per couple off select cruises. Click here for eligible departures.
  • Enjoy a free open-bar cocktail hour every evening before dinner. Click here for eligible departures.
  • Receive free shore excursions on this river cruise. Click here for eligible departures.
  • Save $400 per couple off American Cruise Lines departures when you book nine months in advance. Click here for eligible departures.
  • Receive one free hotel night before American Cruise Lines sailings when you book 9 months in advance. Click here for eligible departures.

Offers subject to change or withdrawal, availability is limited. Some discounts are not combinable.

River Cruise Itinerary
Day 1 St. Louis, MO
Embarkation day. Begin your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens.

Day 2 St. Louis, MO St. Louis, known as the “Gateway to the West,” is sure to win you over. Take in the Gateway Arch Riverfront, highlighted by the majestic Gateway Arch, which is the largest manmade monument in the U.S. There’s something for everyone at St. Louis’ many world-class, free attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens. 

Day 3 Day of River Cruising
Sit back and enjoy the gentle sounds of the paddlewheel as it churns through the placid waters of the Ohio River. One of the highlights of this cruise is the chance to watch the ever-changing scenery pass by and experience the river as early explorers did centuries ago.
 
Day 4 Paducah, KY
From quilting and shopping to learning about Civil War history, there is plenty to do in Paducah. Tour the American Quilt Museum and search for fabrics in the Lower Town Arts District. Shop at Paducah’s galleries. You may also take tours retracing the town's tumultuous Civil War history.

Day 5 New Madrid, MO
Originally founded in 1776 by Spanish Governor Esteban Rodriguez, early settlers of New Madrid were required to become citizens of Spain in order to reside here. Today, New Madrid is a living monument to early American history with sites including the Kochtitsky Home and the Trail of Tears and Veterans Park.

Day 6 Memphis, TN
The largest city in Tennessee offers plenty of attractions. Visit Graceland, and then tour the W.C. Handy Museum; Shelby Farms, the largest urban park in the country; or the “twisted” Ornamental Metal Museum. In the heart of “Blues City,” you’ll find the Peabody Memphis, one of the city’s most popular attractions.

Day 7 Day of River Cruising
As we make our way from historic New Orleans to St. Louis, revel in the sights and sounds of the spectacular Mississippi River. Spend time chatting with other passengers in the lounges or enjoy a cocktail on your private balcony.

Day 8 Vicksburg, MS
From quilting and shopping to learning about Civil War history, there is plenty to do in Paducah. Tour the American Quilt Museum and search for fabrics in the Lower Town Arts District. Shop at Paducah’s galleries. You may also take tours retracing the town's tumultuous Civil War history.

Day 9 Natchez, MS
Perched on a bluff above the Mississippi River, Natchez is a city 300 years in the making. Over 1,000 of its historic structures are listed in the National Register of Historic Places. Upon closer inspection, you will soon discover that Natchez, while indeed a reflection of the past, is also alive in the present, filled with arts, music, culture, events, commerce and natural beauty.

Day 10 Baton Rouge, LA
Experience the wonder of Baton Rouge, Louisiana's capitol. Known as the Red Stick, Baton Rouge is home to legendary Louisiana Cajun cuisine, fascinating plantation tours, and a variety of attractions. There is everything you would expect to find in a state capital, but with a down-home flavor that is part of its seductive charm. Enjoy a grand tour of one of the most historic and unforgettable cities in the South.

Day  11 New Orleans, LA
In New Orleans, explore the French Quarter, with its architectural mix of Spanish, French, Creole, and American styles. Intimate and special, the city’s oldest neighborhood has exerted a spell over writers and artists since the time of Mark Twain, Lafcadio Hern and John James Audubon.
Tour Map
All This Included
Cruise the Mississippi River from the banks of the Bayou to the shores of St. Louis. Your journey starts in the French Quarter, the oldest neighborhood in the vibrant city of New Orleans, brimming with art, music, and culture. Continue to Baton Rouge and Natchez, where you will experience the best in southern hospitality while touring historic homes and grand plantations. Enjoy a captivating lecture from our onboard Civil War historian on your visit to the Vicksburg National Military Park. While in Memphis, take an exclusive tour of the famous Sun Studios, known as the birthplace of Rock n’ Roll. Visit Paducah also known as “Quilt City,” and peruse its many museums and art galleries, before docking at St. Louis, home of The Gateway Arch, our nation’s tallest man-made monument.
  • Dining service, snacks and complimentary cocktail parties.
  • Entertainment aboard the ship.
  • Oversized staterooms – largest in industry.
  • Most with private balconies.
  • Flat screen satellite TV and DVD players in all staterooms.
  • Wireless internet access shipwide.
  • Hairdryers in all staterooms.
  • Individual climate control in all staterooms.
Accommodations on this Tour
Cruising: Category A cabin onboard America or Queen of the Mississippi
Notes
  • Cabin upgrades are available.
  • Itinerary is subject to change.
  • Fares do not include shore tours, gratuities, or port charges and fees.
  • Please ask your Vacations To Go travel counselor for more information.
Terms and Conditions

* The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines. Sorry, we are unable to offer air from countries other than the U.S. However, for those international customers who are able to arrange their own transportation to the trip origination city, we are able to offer the land/cruise portion of the package at the price quoted.



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