American Cruise Lines River Cruise Specialists
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American Cruise Lines

American Cruise Lines specializes in small-ship cruising along the inland waterways and rivers of the United States. Their intriguing itineraries on the Mississippi river and the Columbia and Snake rivers of the Pacific Northwest travel along scenic routes, where passengers get an intimate look at each port visited while enjoying the companionship of fellow travelers and American Cruise Lines' excellent service.

The company's Mississippi paddlewheeler is designed to easily navigate the Mississippi and its tributaries, docking in the heart of each port and taking you where larger ships could never go. Comfortable lounges and large observation decks are ideal for guests to relax, socialize and observe passing scenery and wildlife. Glass-enclosed dining salons provide panoramic views, and spacious staterooms feature large windows and roomy baths.

Onboard entertainment includes guest lecturers, local musicians, theatrical performances and games. A well-stocked library provides reading material and videos highlighting the regions visited. Carefully selected experts use informal lectures, open discussions and activities to share insight about local history, nature and culture.

  • American Cruise Lines offers cruises along the rivers and waterways of the United States.
  • River cruises are rated according to the quality of the vessel and its accommodations, the number of included amenities and activities both on and off the ship, the class of hotels used for land portions of itineraries, and the level of service delivered. American Cruise Lines' sailings are categorized as first class or deluxe on the industry rating scale (budget, first class and deluxe).

Book Now and Save on American Cruise Lines!


  • Save $1,500 per couple off select Mississippi River departures plus enjoy waived port charges when you book by March 29, 2015. Click here for eligible departures.

  • Port charges waived on select Mississippi river cruises. Click here for eligible departures.

  • Enjoy a free open-bar cocktail hour every evening before dinner. Click here for eligible departures.

  • Receive free shore excursions on select river cruises. Click here for eligible departures.

  • Save $400 per couple when you book three months in advance. Click here for eligible departures.

    Click any river cruise below for the itinerary, dates and prices.

    Itinerary Name Days Starts In Ends In Company Quality* From**
    Hudson River (7 Day)   7   New York City, NY   New York City, NY   ACL   1st Class   Dates and Prices
    Mississippi River Cruise (Cincinnati to St. Louis)   8   Cincinnati, OH   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (St. Paul to St. Louis)   8   St. Paul, MN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Fall Foliage, St. Louis to St. Paul)   8   St. Louis, MO   St. Paul, MN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Fall Foliage, St. Paul to St. Louis)   8   St. Paul, MN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Columbia & Snake Rivers (Fall Foliage, Portland to Clarkston)   8   Portland, OR   Clarkston, WA   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Fall Foliage, Clarkston to Portland)   8   Clarkston, WA   Portland, OR   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Portland to Clarkston)   8   Portland, OR   Clarkston, WA   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Clarkston to Portland)   8   Clarkston, WA   Portland, OR   ACL   1st Class   Dates and Prices
    Great Rivers of Florida   8   Jacksonville, FL   Jacksonville, FL   ACL   1st Class   Dates and Prices
    Mississippi River Cruise (St. Louis to St. Paul)   8   St. Louis, MO   St. Paul, MN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (St. Louis to Cincinnati)   8   St. Louis, MO   Cincinnati, OH   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Memphis to St. Louis)   8   Memphis,TN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Memphis to Nashville)   8   Memphis,TN   Nashville, TN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (New Orleans to Memphis)   8   New Orleans, LA   Memphis,TN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Memphis to New Orleans)   8   Memphis,TN   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (New Orleans Roundtrip)   8   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Nashville to St. Louis)   8   Nashville, TN   St. Louis, MO   ACL   1st Class   Dates and Prices
    Hudson River (8 Day)   8   New York City, NY   New York City, NY   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Lewis and Clark Themed Cruise, Portland to Clarkston)   8   Portland, OR   Clarkston, WA   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Lewis and Clark Themed Cruise, Clarkston to Portland)   8   Clarkston, WA   Portland, OR   ACL   1st Class   Dates and Prices
    Mississippi River Cruise (Civil War Cruise, New Orleans to Memphis)   8   New Orleans, LA   Memphis,TN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Civil War Cruise, Memphis to New Orleans)   8   Memphis,TN   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Music Cruise, Memphis to New Orleans)   8   Memphis,TN   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Civil War Cruise, New Orleans Roundtrip)   8   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (Mark Twain Tribute Cruise, St. Paul to St. Louis)   8   St. Paul, MN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Columbia & Snake Rivers (Wine Cruise, Clarkston to Portland)   8   Clarkston, WA   Portland, OR   ACL   1st Class   Dates and Prices
    Columbia & Snake Rivers (Wine Cruise, Portland to Clarkston)   8   Portland, OR   Clarkston, WA   ACL   1st Class   Dates and Prices
    Heartland Celebration (New Orleans to St. Louis)   15   New Orleans, LA   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Complete Mississippi River Cruise   22   New Orleans, LA   St. Paul, MN   ACL   Deluxe   Dates and Prices

    * Key to Quality Ratings

    Tours are classified according to the quality of amenities and accommodations.

    Budget = River cruises typically range from $100 to $200 per person, per day, plus airfare.
    First Class = River cruises typically range from $150 to $350 per person, per day, plus airfare.
    Deluxe = River cruises typically range from $250 to $650 per person, per day, plus airfare.

    ** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines. Sorry, we are unable to offer air from countries other than the U.S. However, for those international customers who are able to arrange their own transportation to the trip origination city, we are able to offer the land/cruise portion of the package at the price quoted.


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    Open Mon-Fri 7am to 10pm, Sat 8am to 8pm, Sun 9am to 8pm, CDT
    River Cruise a division of Vacations To Go