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Mississippi River Cruises

Explore America's true historic treasures on a cruise of the Mississippi River and its tributaries. This 2,320-mile waterway flows through 10 states, from northern Minnesota to the Gulf of Mexico. Its name comes from the Ojibwe word Misi-ziibi, meaning "Great River."

The Mississippi led explorers to new lands, and it served as an important lifeline for the transport of people and goods to the towns that rapidly grew along its banks. Centers of commerce and culture flourished along its main route and tributaries. Cities like St. Louis, Memphis, Vicksburg and New Orleans owe their existence to the Mississippi.

Step back to a time when life moved a little slower and riverboats slowly churned the waters. See Civil War battlefields, restored plantations, rolling farmland and picturesque riverfront towns filled with Victorian-era architecture. The region has a rich musical legacy as the birthplace of the blues, jazz and country music. It's been celebrated in literature, too, most notably by Mark Twain, who grew up in the port town of Hannibal, MO.

Sailings might spend time on the mighty Mississippi in addition to other waterways, like the Tennessee, Ohio, Illinois and Cumberland Rivers. Cruises are particularly good values, because your stateroom and onboard meals are included in a single rate that you pay upfront.


Book Now and Save on Mississippi River Cruises!


  • Save up to $2,200 per couple off 2020 American Queen Steamboat Company cruises. Enjoy additional savings in higher cabin categories. Click here for eligible departures.

  • Book 2021 sailings at 2020 prices, plus save up to an additional $600 per couple in certain cabin categories with American Queen Steamboat Company. Click here for eligible departures.

  • Save up to $2,000 per couple off select American Cruise Lines sailings. Click here for eligible departures.

  • Enjoy free shore excursions on every sailing with American Queen Steamboat Company. Click here for eligible departures.

  • Save $400 per couple off American Cruise Lines departures when you book nine months in advance. Click here for eligible departures.

  • Receive one free hotel night before your cruise with American Cruise Lines, plus transfers to your ship on the day of departure when you book one month in advance. Click here for eligible departures.

  • Receive free shore excursions on select American Cruise Lines river cruises. Click here for eligible departures.

  • Enjoy a free open-bar cocktail hour every evening before dinner with American Cruise Lines. Click here for eligible departures.

    River cruises are rated according to the quality of the vessel and its accommodations, the number of included amenities and activities both on and off the ship, the class of hotels used for land portions of itineraries, and the level of service delivered. The river cruises below are categorized according to the industry rating scale (budget, first class and deluxe). Click any cruise name for the itinerary, dates and prices.

    Itinerary Name Days Starts In Ends In Company Quality* From**
    Mark Twain's Mississippi (American Queen, Alton/St. Louis to Red Wing/Minneapolis)   9   Alton, IL   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Civil War (American Countess, Chattanooga to Memphis)   8   Chattanooga, TN   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Chattanooga to Memphis 2021 (American Duchess)   9   Chattanooga, TN   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Civil War 2021 (Chattanooga to Memphis, American Countess)   9   Chattanooga, TN   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Chattanooga to Memphis 2021 (9 Day, American Queen)   9   Chattanooga, TN   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Kentucky Derby Cruise (American Duchess)   9   Cincinnati, OH   Louisville, KY   Steamboat   Deluxe   Dates and Prices
    Kentucky Derby Cruise 2021 (American Duchess)   9   Cincinnati, OH   Louisville, KY   Steamboat   Deluxe   Dates and Prices
    Louisville to Alton/St. Louis 2021 (9 Day, American Queen)   9   Louisville, KY   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Louisville to Alton 2021 (American Duchess)   9   Louisville, KY   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Louisville to Pittsburgh 2021 (9 Day, American Queen)   9   Louisville, KY   Pittsburgh, PA   Steamboat   Deluxe   Dates and Prices
    Louisville to St. Louis 2021 (American Duchess)   9   Louisville, KY   St. Louis, MO   Steamboat   Deluxe   Dates and Prices
    Louisville to Memphis 2021 (9 Day, American Queen)   9   Louisville, KY   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Civil War (American Countess, Memphis to Chattanooga)   8   Memphis,TN   Chattanooga, TN   Steamboat   Deluxe   Dates and Prices
    Antebellum South (Memphis to New Orleans, American Countess)   8   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Lower Mississippi River Cruise (Memphis to New Orleans)   8   Memphis,TN   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Antebellum South (Memphis to New Orleans, American Countess)   8   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    American River BBQ Challenge (American Countess, Memphis to Alton/St. Louis)   8   Memphis,TN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Lower Mississippi River Cruise (Thanksgiving Cruise, Memphis to New Orleans)   8   Memphis,TN   New Orleans, LA   ACL   Deluxe   Dates and Prices
    American River BBQ Challenge (American Queen, Memphis to Alton/St. Louis)   9   Memphis,TN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Plantation Thanksgiving (Memphis to New Orleans, American Duchess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Plantation Holidays (Memphis to New Orleans, American Duchess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Creole Christmas (American Duchess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Civil War (Memphis to New Orleans, American Queen)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Plantation Holidays (American Queen, Memphis to New Orleans)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South (Memphis to New Orleans, American Duchess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South (Memphis to New Orleans, American Queen)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    American River BBQ Challenge (Memphis to Alton/St. Louis, American Duchess)   9   Memphis,TN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    American River BBQ Challenge 2021 (Memphis to Alton/St. Louis, American Countess)   9   Memphis,TN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Memphis to Louisville 2021 (9 Day, American Queen)   9   Memphis,TN   Louisville, KY   Steamboat   Deluxe   Dates and Prices
    Memphis to Chattanooga 2021 (American Duchess)   9   Memphis,TN   Chattanooga, TN   Steamboat   Deluxe   Dates and Prices
    Antebellum South 2021 (Memphis to New Orleans, American Duchess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South 2021 (Memphis to New Orleans, American Countess)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Civil War 2021 (Memphis to Chattanooga, American Countess)   9   Memphis,TN   Chattanooga, TN   Steamboat   Deluxe   Dates and Prices
    Memphis to New Orleans 2021 (9 Day, American Queen)   9   Memphis,TN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Memphis to Chattanooga 2021 (9 Day, American Queen)   9   Memphis,TN   Chattanooga, TN   Steamboat   Deluxe   Dates and Prices
    Roundtrip Red Wing (Minneapolis) 2021 (American Duchess)   8   Minneapolis, MN   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Mark Twain's Mississippi (Red Wing/Minneapolis to Alton/St. Louis, American Duchess)   8   Minneapolis, MN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Mark Twain's Mississippi (American Queen, Red Wing/Minneapolis to Alton/St. Louis)   9   Minneapolis, MN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    Heartland Heritage (Red Wing/Minneapolis Roundtrip, American Duchess)   9   Minneapolis, MN   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Red Wing/Minneapolis to St. Louis (9 Day, American Countess)   9   Minneapolis, MN   St. Louis, MO   Steamboat   Deluxe   Dates and Prices
    The Mighty Mississippi (American Queen, Red Wing/Minneapolis to New Orleans)   16   Minneapolis, MN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    The Mighty Mississippi (Red Wing/Minneapolis to New Orleans, American Duchess)   16   Minneapolis, MN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Cumberland River Cruise (Fall Foliage, Nashville to St. Louis)   8   Nashville, TN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    American Music Cruise (Nashville to Memphis, American Duchess)   9   Nashville, TN   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Highlights of the Mississippi River   5   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Roundtrip New Orleans 2021 (6 Day, American Countess)   6   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    New Year's Celebration (New Orleans Roundtrip, American Duchess)   8   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Lower Mississippi River Cruise (New Orleans to Memphis)   8   New Orleans, LA   Memphis,TN   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (New Orleans Roundtrip)   8   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Antebellum South (New Orleans to Memphis, American Countess)   8   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Southern Sampler (New Orleans Roundtrip, American Countess)   8   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    New Year's Celebration (New Orleans Roundtrip, American Countess)   8   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Mississippi River Cruise (Christmas Cruise, New Orleans Roundtrip)   8   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Mississippi River Cruise (New Years Cruise, New Orleans Roundtrip)   8   New Orleans, LA   New Orleans, LA   ACL   Deluxe   Dates and Prices
    Plantation Holidays (New Orleans to Memphis, American Duchess)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Plantation Thanksgiving (New Orleans to Memphis)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Plantation Holidays (American Queen, New Orleans to Memphis)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Creole Christmas (American Queen)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    New Year's Celebration (American Queen)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South (New Orleans to Memphis, American Duchess)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Southern Sampler (American Queen)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Southern Sampler (New Orleans Roundtrip, American Duchess)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Mardi Gras on the River (American Queen)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Antebellum South (New Orleans to Memphis, American Queen)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Southern Sampler 2021 (New Orleans Roundtrip, American Duchess)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South 2021 (New Orleans to Memphis, American Duchess)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Roundtrip New Orleans 2021 (9 Day, American Countess)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Roundtrip New Orleans 2021 (9 Day, American Queen)   9   New Orleans, LA   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Antebellum South 2021 (New Orleans to Memphis, American Countess)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    New Orleans to Memphis 2021 (9 Day, American Queen)   9   New Orleans, LA   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    Mississippi River Gateway Cruise (New Orleans to St. Louis)   11   New Orleans, LA   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Complete Mississippi River Cruise   22   New Orleans, LA   St. Paul, MN   ACL   Deluxe   Dates and Prices
    The Mighty Mississippi (New Orleans to Red Wing, American Duchess)   23   New Orleans, LA   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Pittsburgh to Louisville 2021 (9 Day, American Queen)   9   Pittsburgh, PA   Louisville, KY   Steamboat   Deluxe   Dates and Prices
    Mark Twain's Mississippi (American Countess, Red Wing/Minneapolis to Alton/St. Louis)   8   Red Wing, MN   Alton, IL   Steamboat   Deluxe   Dates and Prices
    The Mighty Mississippi (Red Wing to New Orleans, American Countess)   15   Red Wing, MN   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Alton (St. Louis) to Red Wing (Minneapolis) 2021 (American Duchess)   8   St. Louis, MO   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Mark Twain's Mississippi (Alton/St. Louis to Red Wing/Minneapolis)   8   St. Louis, MO   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Upper Mississippi River Cruise (St. Louis to St. Paul)   8   St. Louis, MO   St. Paul, MN   ACL   Deluxe   Dates and Prices
    Mark Twain Upper Mississippi River Cruise (St. Louis to St. Paul)   8   St. Louis, MO   St. Paul, MN   ACL   Deluxe   Dates and Prices
    Mark Twain's Mississippi (Alton/St. Louis to Red Wing/Minneapolis, American Duchess)   8   St. Louis, MO   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Cumberland River Cruise (Fall Foliage, St. Louis to Nashville)   8   St. Louis, MO   Nashville, TN   ACL   Deluxe   Dates and Prices
    American River BBQ Challenge (St. Louis/Alton to Memphis, American Duchess)   9   St. Louis, MO   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    American Culinary Experience (St. Louis to Cincinnati, American Duchess)   9   St. Louis, MO   Cincinnati, OH   Steamboat   Deluxe   Dates and Prices
    Alton (St. Louis) to Memphis 2021 (American Duchess)   9   St. Louis, MO   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    American Culinary Experience 2021 (St. Louis to Cincinnati, American Duchess)   9   St. Louis, MO   Cincinnati, OH   Steamboat   Deluxe   Dates and Prices
    Mark Twain's Mississippi 2021 (Alton/St. Louis to Red Wing/Minneapolis, American Countess)   9   St. Louis, MO   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    St. Louis to Memphis 2021 (American Duchess)   9   St. Louis, MO   Memphis,TN   Steamboat   Deluxe   Dates and Prices
    St. Louis to New Orleans 2021 (9 Day, American Countess)   9   St. Louis, MO   New Orleans, LA   Steamboat   Deluxe   Dates and Prices
    Alton/St. Louis to Red Wing/Minneapolis 2021 (9 Day, American Queen)   9   St. Louis, MO   Red Wing, MN   Steamboat   Deluxe   Dates and Prices
    Upper Mississippi River Cruise (St. Paul to St. Louis)   8   St. Paul, MN   St. Louis, MO   ACL   Deluxe   Dates and Prices
    Grand Heartland Cruise   15   St. Paul, MN   New Orleans, LA   ACL   Deluxe   Dates and Prices

    * Key to Quality Ratings

    Tours are classified according to the quality of amenities and accommodations.

    Budget = River cruises typically range from $100 to $200 per person, per day, plus airfare.
    First Class = River cruises typically range from $150 to $350 per person, per day, plus airfare.
    Deluxe = River cruises typically range from $250 to $650 per person, per day, plus airfare.

    ** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines. Sorry, we are unable to offer air from countries other than the U.S. However, for those international customers who are able to arrange their own transportation to the trip origination city, we are able to offer the land/cruise portion of the package at the price quoted.


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